Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
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1608 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R1201 | DB09049 | approved | small molecule | Naloxegol | Indication associated | Details |
| R1202 | DB09050 | approved; investigational | small molecule | Ceftolozane | Indication associated | Details |
| R1203 | DB09052 | approved; investigational | biotech | Blinatumomab | Therapeutic strategy associated | Details |
| R1204 | DB09053 | approved | small molecule | Ibrutinib | Therapeutic strategy associated | Details |
| R1205 | DB09054 | approved | small molecule | Idelalisib | Therapeutic strategy associated | Details |
| R1206 | DB09059 | approved; investigational | small molecule | Atosiban | Therapeutic strategy associated | Details |
| R1207 | DB09060 | approved | small molecule | Avibactam | Indication associated | Details |
| R1208 | DB09061 | approved; investigational | small molecule | Cannabidiol | Therapeutic strategy associated | Details |
| R1209 | DB09064 | approved; investigational | small molecule | Ciprofibrate | Target associated | Details |
| R1210 | DB09069 | approved; investigational | small molecule | Trimetazidine | Indication associated | Details |
| R1211 | DB09070 | approved; investigational | small molecule | Tibolone | Therapeutic strategy associated | Details |
| R1212 | DB09075 | approved | small molecule | Edoxaban | Indication associated | Details |
| R1213 | DB09077 | approved; investigational | biotech | Dinutuximab | Therapeutic strategy associated | Details |
| R1214 | DB09079 | approved | small molecule | Nintedanib | Therapeutic strategy associated | Details |
| R1215 | DB09083 | approved | small molecule | Ivabradine | Indication associated | Details |
| R1216 | DB09084 | approved | small molecule | Benzydamine | Therapeutic strategy associated | Details |
| R1217 | DB09086 | approved | small molecule | Eugenol | Therapeutic strategy associated | Details |
| R1218 | DB09087 | approved | small molecule | Potassium alum | Indication associated | Details |
| R1219 | DB09089 | approved | small molecule | Trimebutine | Indication associated | Details |
| R1220 | DB09090 | approved | small molecule | Pinaverium | Indication associated | Details |
| R1221 | DB09092 | approved; withdrawn | small molecule | Xanthinol | Indication associated | Details |
| R1222 | DB09095 | approved; investigational; withdrawn | small molecule | Difluocortolone | Therapeutic strategy associated | Details |
| R1223 | DB09099 | approved; investigational | small molecule | Somatostatin | Therapeutic strategy associated | Details |
| R1224 | DB09100 | approved | biotech | Thyroid, porcine | Target associated | Details |
| R1225 | DB09104 | approved; investigational | small molecule | Magnesium hydroxide | Therapeutic strategy associated | Details |
| R1226 | DB09110 | approved; investigational | small molecule | Coenzyme M | Therapeutic strategy associated | Details |
| R1227 | DB09114 | approved; investigational; withdrawn | small molecule | Colfosceril palmitate | Indication associated | Details |
| R1228 | DB09120 | approved; investigational | small molecule | Zucapsaicin | Therapeutic strategy associated | Details |
| R1229 | DB09121 | approved; withdrawn | small molecule | Aurothioglucose | Therapeutic strategy associated | Details |
| R1230 | DB09124 | approved; withdrawn | small molecule | Medrogestone | Therapeutic strategy associated | Details |
| R1231 | DB09130 | approved; investigational | small molecule | Copper | Therapeutic strategy associated | Details |
| R1232 | DB09134 | approved | small molecule | Ioversol | Indication associated | Details |
| R1233 | DB09139 | approved | small molecule | Technetium Tc-99m oxidronate | Indication associated | Details |
| R1234 | DB09140 | approved; vet_approved | small molecule | Oxygen | Therapeutic strategy associated | Details |
| R1235 | DB09163 | approved | small molecule | Technetium Tc-99m exametazime | Indication associated | Details |
| R1236 | DB09165 | approved | small molecule | Technetium Tc-99m pyrophosphate | Indication associated | Details |
| R1237 | DB09166 | experimental | small molecule | Etizolam | Therapeutic strategy associated | Details |
| R1238 | DB09185 | approved; investigational; withdrawn | small molecule | Viloxazine | Indication associated | Details |
| R1239 | DB09194 | withdrawn | small molecule | Etoperidone | Indication associated | Details |
| R1240 | DB09201 | experimental | small molecule | Ciglitazone | Target associated | Details |
| R1241 | DB09204 | investigational | small molecule | Arotinolol | Therapeutic strategy associated | Details |
| R1242 | DB09210 | approved; investigational | small molecule | Piracetam | Therapeutic strategy associated | Details |
| R1243 | DB09212 | approved | small molecule | Loxoprofen | Therapeutic strategy associated | Details |
| R1244 | DB09213 | approved; investigational | small molecule | Dexibuprofen | Therapeutic strategy associated | Details |
| R1245 | DB09214 | approved; investigational | small molecule | Dexketoprofen | Therapeutic strategy associated | Details |
| R1246 | DB09215 | withdrawn | small molecule | Droxicam | Therapeutic strategy associated | Details |
| R1247 | DB09216 | approved; investigational | small molecule | Tolfenamic acid | Therapeutic strategy associated | Details |
| R1248 | DB09218 | experimental | small molecule | Clonixin | Therapeutic strategy associated | Details |
| R1249 | DB09219 | approved | small molecule | Bisoxatin | Indication associated | Details |
| R1250 | DB09220 | approved; investigational | small molecule | Nicorandil | Indication associated | Details |
| R1251 | DB09221 | experimental | small molecule | Polaprezinc | Therapeutic strategy associated | Details |
| R1252 | DB09227 | experimental | small molecule | Barnidipine | Therapeutic strategy associated | Details |
| R1253 | DB09229 | experimental | small molecule | Aranidipine | Indication associated | Details |
| R1254 | DB09230 | investigational | small molecule | Azelnidipine | Therapeutic strategy associated | Details |
| R1255 | DB09231 | experimental | small molecule | Benidipine | Indication associated | Details |
| R1256 | DB09232 | investigational | small molecule | Cilnidipine | Indication associated | Details |
| R1257 | DB09235 | experimental | small molecule | Efonidipine | Therapeutic strategy associated | Details |
| R1258 | DB09236 | approved; investigational | small molecule | Lacidipine | Therapeutic strategy associated | Details |
| R1259 | DB09237 | approved; investigational | small molecule | Levamlodipine | Indication associated | Details |
| R1260 | DB09238 | approved; investigational | small molecule | Manidipine | Therapeutic strategy associated | Details |
| R1261 | DB09241 | approved; investigational | small molecule | Methylene blue | Therapeutic strategy associated | Details |
| R1262 | DB09243 | experimental | small molecule | Hydracarbazine | Indication associated | Details |
| R1263 | DB09244 | experimental | small molecule | Pirlindole | Indication associated | Details |
| R1264 | DB09246 | withdrawn | small molecule | Benmoxin | Indication associated | Details |
| R1265 | DB09247 | withdrawn | small molecule | Iproclozide | Indication associated | Details |
| R1266 | DB09248 | withdrawn | small molecule | Mebanazine | Indication associated | Details |
| R1267 | DB09249 | withdrawn | small molecule | Octamoxin | Indication associated | Details |
| R1268 | DB09250 | withdrawn | small molecule | Pheniprazine | Indication associated | Details |
| R1269 | DB09251 | withdrawn | small molecule | Phenoxypropazine | Indication associated | Details |
| R1270 | DB09252 | withdrawn | small molecule | Pivhydrazine | Indication associated | Details |
| R1271 | DB09253 | withdrawn | small molecule | Safrazine | Indication associated | Details |
| R1272 | DB09254 | withdrawn | small molecule | Caroxazone | Indication associated | Details |
| R1273 | DB09260 | approved; investigational | small molecule | Parnaparin | Indication associated | Details |
| R1274 | DB09261 | approved; investigational | small molecule | Certoparin | Indication associated | Details |
| R1275 | DB09265 | approved | small molecule | Lixisenatide | Target associated | Details |
| R1276 | DB09267 | approved; withdrawn | small molecule | Strontium ranelate | Therapeutic strategy associated | Details |
| R1277 | DB09272 | approved; investigational | small molecule | Eluxadoline | Indication associated | Details |
| R1278 | DB09273 | experimental | small molecule | Doxofylline | Therapeutic strategy associated | Details |
| R1279 | DB09276 | approved; investigational | small molecule | Sodium aurothiomalate | Indication associated | Details |
| R1280 | DB09279 | investigational | small molecule | Fimasartan | Therapeutic strategy associated | Details |
| R1281 | DB09282 | approved; investigational | small molecule | Molsidomine | Therapeutic strategy associated | Details |
| R1282 | DB09284 | investigational | small molecule | Imolamine | Indication associated | Details |
| R1283 | DB09285 | experimental | small molecule | Morniflumate | Therapeutic strategy associated | Details |
| R1284 | DB09287 | approved; vet_approved | small molecule | Polyethylene glycol | Indication associated | Details |
| R1285 | DB09288 | experimental | small molecule | Propacetamol | Therapeutic strategy associated | Details |
| R1286 | DB09290 | investigational | small molecule | Ramosetron | Indication associated | Details |
| R1287 | DB09291 | approved; investigational | small molecule | Rolapitant | Therapeutic strategy associated | Details |
| R1288 | DB09292 | approved | small molecule | Sacubitril | Indication associated | Details |
| R1289 | DB09295 | experimental | small molecule | Talniflumate | Indication associated | Details |
| R1290 | DB09301 | approved; investigational; nutraceutical | small molecule | Chondroitin sulfate | Therapeutic strategy associated | Details |
| R1291 | DB09302 | approved | biotech | Alirocumab | Indication associated | Details |
| R1292 | DB09303 | approved | biotech | Evolocumab | Indication associated | Details |
| R1293 | DB09304 | experimental | small molecule | Setiptiline | Indication associated | Details |
| R1294 | DB09305 | experimental | small molecule | Aptazapine | Indication associated | Details |
| R1295 | DB09306 | experimental | small molecule | Metralindole | Indication associated | Details |
| R1296 | DB09307 | experimental | small molecule | Oxaprotiline | Indication associated | Details |
| R1297 | DB09311 | experimental | small molecule | Polycarbophil | Indication associated | Details |
| R1298 | DB09320 | approved; vet_approved | small molecule | Procaine benzylpenicillin | Indication associated | Details |
| R1299 | DB09324 | approved | small molecule | Sulbactam | Indication associated | Details |
| R1300 | DB09328 | approved; investigational | biotech | Vayarin | Indication associated | Details |