CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of NAFLD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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34330 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C02104 | BRD-A85891951 | BRD-A85891951 | -- | -- | -- | Details |
| C02105 | BRD-A86044036 | flurbiprofen | -- | -- | flurbiprofen-(+/-) | Details |
| C02106 | BRD-A86109770 | guggulsterone | NR3C1; AR; NR3C2; PGR; NR1H4 | IKK inhibitor; FXR antagonist; Cholesterol inhibitor; Estrogen receptor agonist; Pregnane X receptor agonist; Progesterone receptor agonist | -- | Details |
| C02107 | BRD-A86146706 | BRD-A86146706 | -- | -- | -- | Details |
| C02108 | BRD-A86216746 | varenicline | CHRNA4 | Acetylcholine receptor agonist | -- | Details |
| C02109 | BRD-A86248581 | tetrahydrouridine | CDA | Cytidine deaminase inhibitor | -- | Details |
| C02110 | BRD-A86414188 | ractopamine | -- | -- | -- | Details |
| C02111 | BRD-A86415025 | BRD-A86415025 | -- | -- | 1-(1,2-diphenylethyl)piperidine-(+/-) | Details |
| C02112 | BRD-A86550573 | BRD-A86550573 | -- | -- | -- | Details |
| C02113 | BRD-A86619021 | BRD-A86619021 | -- | -- | andrographolide | Details |
| C02114 | BRD-A86629089 | BRD-A86629089 | -- | -- | -- | Details |
| C02115 | BRD-A86748098 | BRD-A86748098 | -- | -- | -- | Details |
| C02116 | BRD-A86792397 | BRD-A86792397 | -- | -- | -- | Details |
| C02117 | BRD-A86871940 | nicaraven | -- | -- | -- | Details |
| C02118 | BRD-A86977540 | BRD-A86977540 | -- | -- | -- | Details |
| C02119 | BRD-A86990971 | KUC103424N | -- | -- | KUC-103424N | Details |
| C02120 | BRD-A87125127 | 3-matida | GRM1 | Glutamate receptor antagonist | 3-MATIDA | Details |
| C02121 | BRD-A87130939 | masoprocol | ALOX5 | Lipoxygenase inhibitor | -- | Details |
| C02122 | BRD-A87137733 | GSK-690693 | AKT3; AKT1; AKT2; PRKCQ | Akt inhibitor | -- | Details |
| C02123 | BRD-A87325732 | BRD-A87325732 | -- | -- | -- | Details |
| C02124 | BRD-A87384553 | BRD-A87384553 | -- | -- | -- | Details |
| C02125 | BRD-A87387433 | cefpodoxime | -- | -- | -- | Details |
| C02126 | BRD-A87435144 | AZD-7545 | -- | -- | -- | Details |
| C02127 | BRD-A87445400 | yohimbine | ADRA2A; ADRA2B; ADRA2C; HTR1A; HTR1B; HTR1D; HTR2B | Adrenergic receptor antagonist | -- | Details |
| C02128 | BRD-A87455648 | BRD-A87455648 | -- | -- | -- | Details |
| C02129 | BRD-A87479750 | tenidap | -- | -- | -- | Details |
| C02130 | BRD-A87494167 | BRD-A87494167 | -- | -- | -- | Details |
| C02131 | BRD-A87606379 | nadolol | ADRB1; ADRB2 | Adrenergic receptor antagonist | -- | Details |
| C02132 | BRD-A87715314 | pronetalol | -- | -- | -- | Details |
| C02133 | BRD-A87719232 | naproxen | PTGS1; PTGS2 | Cyclooxygenase inhibitor | -- | Details |
| C02134 | BRD-A87848830 | bimatoprost | PTGFR | Prostanoid receptor agonist | -- | Details |
| C02135 | BRD-A87983072 | benzotript | CCKAR; CCKBR | CCK receptor antagonist | -- | Details |
| C02136 | BRD-A88029023 | BRD-A88029023 | -- | -- | -- | Details |
| C02137 | BRD-A88080608 | equilin | HSD17B1 | Estrogen receptor agonist | -- | Details |
| C02138 | BRD-A88138582 | halcinonide | NR3C1 | Glucocorticoid receptor agonist | -- | Details |
| C02139 | BRD-A88208128 | tetracycline | -- | -- | -- | Details |
| C02140 | BRD-A88237615 | BRD-A88237615 | -- | -- | -- | Details |
| C02141 | BRD-A88254928 | salbutamol | ADRB2 | Adrenergic receptor agonist | -- | Details |
| C02142 | BRD-A88282067 | delcorine | -- | -- | -- | Details |
| C02143 | BRD-A88369366 | trelagliptin | DPP4 | Dipeptidyl peptidase inhibitor | -- | Details |
| C02144 | BRD-A88381870 | BRD-A88381870 | -- | -- | -- | Details |
| C02145 | BRD-A88461048 | BRD-A88461048 | -- | -- | -- | Details |
| C02146 | BRD-A88504692 | BRD-A88504692 | -- | -- | -- | Details |
| C02147 | BRD-A88548664 | SKF-38393 | DRD1; DRD5 | Dopamine receptor agonist | -- | Details |
| C02148 | BRD-A88691416 | BRD-A88691416 | -- | -- | -- | Details |
| C02149 | BRD-A88765664 | BRD-A88765664 | -- | -- | -- | Details |
| C02150 | BRD-A88774919 | doxycycline | MMP8 | Metalloproteinase inhibitor | -- | Details |
| C02151 | BRD-A88878656 | BRD-A88878656 | -- | -- | -- | Details |
| C02152 | BRD-A88939772 | estriol | ESR1; ESR2 | Estrogen receptor agonist | -- | Details |
| C02153 | BRD-A89038047 | BRD-A89038047 | -- | -- | -- | Details |
| C02154 | BRD-A89047717 | KU-C103654 | -- | -- | -- | Details |
| C02155 | BRD-A89049230 | BRD-A89049230 | TSHR | Thyroid hormone stimulant | -- | Details |
| C02156 | BRD-A89067742 | BRD-A89067742 | -- | -- | -- | Details |
| C02157 | BRD-A89104433 | VU-0415556-1 | -- | -- | -- | Details |
| C02158 | BRD-A89164055 | sorbinil | AKR1B1 | Aldose reductase inhibitor | -- | Details |
| C02159 | BRD-A89175223 | bisoprolol | ADRB1 | Adrenergic receptor antagonist | -- | Details |
| C02160 | BRD-A89196962 | dalargin | OPRM1 | Opioid receptor agonist | -- | Details |
| C02161 | BRD-A89208012 | BRD-A89208012 | -- | -- | -- | Details |
| C02162 | BRD-A89237309 | BRD-A89237309 | -- | -- | -- | Details |
| C02163 | BRD-A89333723 | BRD-A89333723 | -- | -- | -- | Details |
| C02164 | BRD-A89337244 | PD-102807 | CHRM4 | Acetylcholine receptor antagonist | -- | Details |
| C02165 | BRD-A89352139 | STK-111867 | -- | -- | -- | Details |
| C02166 | BRD-A89354030 | BRD-A89354030 | -- | -- | -- | Details |
| C02167 | BRD-A89407846 | BRD-A89407846 | -- | -- | -- | Details |
| C02168 | BRD-A89434049 | sarmentogenin | -- | -- | -- | Details |
| C02169 | BRD-A89441445 | BRD-A89441445 | -- | -- | -- | Details |
| C02170 | BRD-A89471191 | BRD-A89471191 | -- | -- | -- | Details |
| C02171 | BRD-A89471977 | BRD-A89471977 | -- | -- | -- | Details |
| C02172 | BRD-A89494828 | BRD-A89494828 | -- | -- | -- | Details |
| C02173 | BRD-A89499670 | BRD-A89499670 | -- | -- | -- | Details |
| C02174 | BRD-A89554862 | BRD-A89554862 | -- | -- | -- | Details |
| C02175 | BRD-A89575866 | BRD-A89575866 | -- | -- | -- | Details |
| C02176 | BRD-A89585551 | mefloquine | -- | -- | -- | Details |
| C02177 | BRD-A89672324 | CGP-55845 | GABBR1; GABBR2 | GABA receptor antagonist | -- | Details |
| C02178 | BRD-A89681034 | BRD-A89681034 | -- | -- | -- | Details |
| C02179 | BRD-A89846380 | BRD-A89846380 | -- | -- | -- | Details |
| C02180 | BRD-A89859721 | BRD-A89859721 | -- | -- | -- | Details |
| C02181 | BRD-A89907244 | BRD-A89907244 | -- | -- | -- | Details |
| C02182 | BRD-A89947015 | BRD-A89947015 | -- | -- | -- | Details |
| C02183 | BRD-A89983325 | BRD-A89983325 | -- | -- | -- | Details |
| C02184 | BRD-A90131694 | alclometasone | NR3C1 | Glucocorticoid receptor agonist | -- | Details |
| C02185 | BRD-A90249268 | BRD-A90249268 | -- | -- | -- | Details |
| C02186 | BRD-A90289676 | BRD-A90289676 | -- | -- | -- | Details |
| C02187 | BRD-A90311807 | cilastatin | DPEP1 | Dehydropeptidase inhibitor | -- | Details |
| C02188 | BRD-A90450579 | BRD-A90450579 | -- | -- | -- | Details |
| C02189 | BRD-A90451247 | KU-60019 | ATM | ATM kinase inhibitor | -- | Details |
| C02190 | BRD-A90462498 | BRD-A90462498 | -- | -- | -- | Details |
| C02191 | BRD-A90490067 | fulvestrant | ESR1 | Estrogen receptor antagonist | -- | Details |
| C02192 | BRD-A90515964 | guaifenesin | -- | -- | -- | Details |
| C02193 | BRD-A90521842 | mecamylamine-hcl | -- | -- | -- | Details |
| C02194 | BRD-A90543464 | BRD-A90543464 | -- | -- | -- | Details |
| C02195 | BRD-A90547603 | eptifibatide | ITGA2B; ITGB3 | Platelet aggregation inhibitor | -- | Details |
| C02196 | BRD-A90551241 | lornoxicam | PTGS1; PTGS2 | Cyclooxygenase inhibitor | -- | Details |
| C02197 | BRD-A90625545 | clinofibrate | LPL | Lipase clearing factor inhibitor | -- | Details |
| C02198 | BRD-A90643929 | BRD-A90643929 | -- | -- | -- | Details |
| C02199 | BRD-A90695733 | manidipine | CACNA1C | Calcium channel blocker | -- | Details |
| C02200 | BRD-A90799790 | isradipine | CACNA1C; CACNA1D; CACNA1F; CACNA1S; CACNA2D1 | Calcium channel blocker | -- | Details |
| C02201 | BRD-A90969585 | BRD-A90969585 | -- | -- | -- | Details |
| C02202 | BRD-A91008255 | bepridil | -- | -- | -- | Details |
| C02203 | BRD-A91404865 | BRD-A91404865 | -- | -- | -- | Details |