Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
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1608 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R1301 | DB09331 | approved | biotech | Daratumumab | Therapeutic strategy associated | Details |
| R1302 | DB09338 | experimental | small molecule | Mersalyl | Therapeutic strategy associated | Details |
| R1303 | DB09351 | approved; investigational | small molecule | Levobetaxolol | Indication associated | Details |
| R1304 | DB09357 | approved | small molecule | Dexpanthenol | Therapeutic strategy associated | Details |
| R1305 | DB09363 | investigational | small molecule | Rauwolfia serpentina root | Therapeutic strategy associated | Details |
| R1306 | DB09394 | approved | small molecule | Phosphoric acid | Therapeutic strategy associated | Details |
| R1307 | DB09398 | approved | small molecule | Fluoride ion F-18 | Indication associated | Details |
| R1308 | DB09409 | approved | small molecule | Magnesium acetate tetrahydrate | Indication associated | Details |
| R1309 | DB09422 | approved | biotech | Soybean oil | Therapeutic strategy associated | Details |
| R1310 | DB09446 | approved; investigational | biotech | Safflower oil | Therapeutic strategy associated | Details |
| R1311 | DB09449 | approved | small molecule | Sodium phosphate, monobasic | Indication associated | Details |
| R1312 | DB09462 | approved; investigational | small molecule | Glycerin | Target associated | Details |
| R1313 | DB09477 | approved | small molecule | Enalaprilat | Indication associated | Details |
| R1314 | DB09496 | approved; investigational | small molecule | Octinoxate | Therapeutic strategy associated | Details |
| R1315 | DB09502 | approved; investigational | small molecule | Fludeoxyglucose (18F) | Therapeutic strategy associated | Details |
| R1316 | DB09532 | approved | biotech | Secretin human | Therapeutic strategy associated | Details |
| R1317 | DB09543 | approved; vet_approved | small molecule | Methyl salicylate | Therapeutic strategy associated | Details |
| R1318 | DB09564 | approved | biotech | Insulin degludec | Indication associated | Details |
| R1319 | DB09568 | approved; investigational | small molecule | Omega-3-carboxylic acids | Therapeutic strategy associated | Details |
| R1320 | DB09570 | approved; investigational | small molecule | Ixazomib | Therapeutic strategy associated | Details |
| R1321 | DB10552 | approved | biotech | Peach | Indication associated | Details |
| R1322 | DB10770 | approved | biotech | Foreskin fibroblast (neonatal) | Target associated | Details |
| R1323 | DB10771 | approved | biotech | Bovine type I collagen | Indication associated | Details |
| R1324 | DB10772 | approved | biotech | Foreskin keratinocyte (neonatal) | Target associated | Details |
| R1325 | DB10989 | approved | biotech | Hepatitis A Vaccine | Therapeutic strategy associated | Details |
| R1326 | DB11051 | approved; investigational | biotech | Azficel-T | Therapeutic strategy associated | Details |
| R1327 | DB11068 | approved | small molecule | Selenic acid | Therapeutic strategy associated | Details |
| R1328 | DB11073 | approved | small molecule | Cetylpyridinium | Indication associated | Details |
| R1329 | DB11079 | approved | small molecule | Trolamine salicylate | Therapeutic strategy associated | Details |
| R1330 | DB11086 | approved | biotech | Cocoa butter | Therapeutic strategy associated | Details |
| R1331 | DB11089 | approved | small molecule | Docusate | Indication associated | Details |
| R1332 | DB11095 | approved | biotech | Desirudin | Therapeutic strategy associated | Details |
| R1333 | DB11100 | approved | small molecule | Allantoin | Therapeutic strategy associated | Details |
| R1334 | DB11107 | experimental | small molecule | Potassium bitartrate | Indication associated | Details |
| R1335 | DB11110 | approved | small molecule | Magnesium citrate | Indication associated | Details |
| R1336 | DB11113 | approved; investigational; nutraceutical; vet_approved | biotech | Castor oil | Therapeutic strategy associated | Details |
| R1337 | DB11114 | approved | biotech | Eucalyptus oil | Therapeutic strategy associated | Details |
| R1338 | DB11117 | approved; investigational | small molecule | Undecylenic acid | Therapeutic strategy associated | Details |
| R1339 | DB11120 | approved; experimental | small molecule | Turpentine | Therapeutic strategy associated | Details |
| R1340 | DB11125 | approved | small molecule | Benzethonium | Therapeutic strategy associated | Details |
| R1341 | DB11127 | approved; investigational | small molecule | Selenious acid | Therapeutic strategy associated | Details |
| R1342 | DB11131 | approved | biotech | Capsicum oleoresin | Therapeutic strategy associated | Details |
| R1343 | DB11134 | approved | small molecule | Cupric oxide | Therapeutic strategy associated | Details |
| R1344 | DB11157 | approved | small molecule | Anthralin | Therapeutic strategy associated | Details |
| R1345 | DB11160 | approved | small molecule | Phenyltoloxamine | Therapeutic strategy associated | Details |
| R1346 | DB11164 | approved; investigational | small molecule | Bicisate | Indication associated | Details |
| R1347 | DB11193 | approved | small molecule | Papain | Therapeutic strategy associated | Details |
| R1348 | DB11198 | approved; investigational | biotech | Peppermint oil | Indication associated | Details |
| R1349 | DB11201 | approved | small molecule | Menthyl salicylate | Indication associated | Details |
| R1350 | DB11204 | approved | small molecule | Panthenol | Therapeutic strategy associated | Details |
| R1351 | DB11207 | approved | small molecule | Amiloxate | Therapeutic strategy associated | Details |
| R1352 | DB11217 | approved | small molecule | Arbutin | Therapeutic strategy associated | Details |
| R1353 | DB11218 | experimental; nutraceutical | biotech | Tea tree oil | Therapeutic strategy associated | Details |
| R1354 | DB11228 | approved | small molecule | Methylcellulose | Indication associated | Details |
| R1355 | DB11239 | approved | small molecule | Aluminum sulfate | Therapeutic strategy associated | Details |
| R1356 | DB11242 | approved; vet_approved | small molecule | Gelatin | Indication associated | Details |
| R1357 | DB11251 | approved; investigational | small molecule | Tocopherol | Therapeutic strategy associated | Details |
| R1358 | DB11254 | approved | small molecule | Hexylresorcinol | Therapeutic strategy associated | Details |
| R1359 | DB11256 | approved; investigational | small molecule | Levomefolic acid | Indication associated | Details |
| R1360 | DB11265 | nutraceutical | biotech | Curcuma xanthorrhiza oil | Therapeutic strategy associated | Details |
| R1361 | DB11269 | approved | small molecule | Diethylamino hydroxybenzoyl hexyl benzoate | Therapeutic strategy associated | Details |
| R1362 | DB11296 | experimental | small molecule | Prezatide | Therapeutic strategy associated | Details |
| R1363 | DB11321 | nutraceutical; vet_approved | small molecule | Cod liver oil | Indication associated | Details |
| R1364 | DB11323 | approved | small molecule | Glycol salicylate | Therapeutic strategy associated | Details |
| R1365 | DB11324 | investigational | small molecule | Nonivamide | Therapeutic strategy associated | Details |
| R1366 | DB11332 | approved | small molecule | Sinapultide | Therapeutic strategy associated | Details |
| R1367 | DB11333 | approved; investigational | small molecule | Poloxamer 188 | Therapeutic strategy associated | Details |
| R1368 | DB11338 | approved; nutraceutical | biotech | Clove oil | Therapeutic strategy associated | Details |
| R1369 | DB11358 | investigational; nutraceutical | biotech | Evening primrose oil | Therapeutic strategy associated | Details |
| R1370 | DB11362 | approved | small molecule | Selexipag | Therapeutic strategy associated | Details |
| R1371 | DB11365 | experimental | small molecule | Sennosides | Therapeutic strategy associated | Details |
| R1372 | DB11367 | withdrawn | small molecule | Cefroxadine | Indication associated | Details |
| R1373 | DB11386 | approved; investigational; vet_approved | small molecule | Chlorobutanol | Therapeutic strategy associated | Details |
| R1374 | DB11560 | approved; investigational | small molecule | Lesinurad | Indication associated | Details |
| R1375 | DB11569 | approved; investigational | biotech | Ixekizumab | Therapeutic strategy associated | Details |
| R1376 | DB11580 | approved; investigational | biotech | Ravulizumab | Therapeutic strategy associated | Details |
| R1377 | DB11581 | approved; investigational | small molecule | Venetoclax | Therapeutic strategy associated | Details |
| R1378 | DB11582 | experimental | small molecule | Thiocolchicoside | Target associated | Details |
| R1379 | DB11584 | approved | small molecule | Pipradrol | Therapeutic strategy associated | Details |
| R1380 | DB11588 | approved; investigational | small molecule | Carbon monoxide | Therapeutic strategy associated | Details |
| R1381 | DB11590 | approved | small molecule | Thimerosal | Therapeutic strategy associated | Details |
| R1382 | DB11601 | approved | biotech | Tuberculin purified protein derivative | Therapeutic strategy associated | Details |
| R1383 | DB11605 | approved | small molecule | Myrrh | Therapeutic strategy associated | Details |
| R1384 | DB11611 | approved | small molecule | Lifitegrast | Therapeutic strategy associated | Details |
| R1385 | DB11626 | approved | biotech | Tasonermin | Therapeutic strategy associated | Details |
| R1386 | DB11627 | approved; withdrawn | biotech | Hepatitis B Vaccine (Recombinant) | Indication associated | Details |
| R1387 | DB11635 | approved | small molecule | Tocofersolan | Indication associated | Details |
| R1388 | DB11641 | approved; investigational | small molecule | Vinflunine | Therapeutic strategy associated | Details |
| R1389 | DB11660 | approved; investigational | small molecule | Latanoprostene bunod | Indication associated | Details |
| R1390 | DB11689 | approved; investigational | small molecule | Selumetinib | Therapeutic strategy associated | Details |
| R1391 | DB11691 | approved; investigational | small molecule | Naldemedine | Indication associated | Details |
| R1392 | DB11693 | approved; investigational | small molecule | Voclosporin | Therapeutic strategy associated | Details |
| R1393 | DB11700 | approved; investigational | small molecule | Setmelanotide | Therapeutic strategy associated | Details |
| R1394 | DB11712 | approved; investigational | small molecule | Tezacaftor | Therapeutic strategy associated | Details |
| R1395 | DB11714 | approved; investigational | biotech | Durvalumab | Therapeutic strategy associated | Details |
| R1396 | DB11721 | investigational | small molecule | Mitoglitazone | Target associated | Details |
| R1397 | DB11735 | approved; investigational | small molecule | Galactose | Indication associated | Details |
| R1398 | DB11737 | experimental; investigational | small molecule | Icotinib | Therapeutic strategy associated | Details |
| R1399 | DB11752 | investigational | small molecule | Bryostatin 1 | Target associated | Details |
| R1400 | DB11753 | approved; investigational | small molecule | Rifamycin | Therapeutic strategy associated | Details |