Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
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1608 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R0901 | DB05939 | investigational | small molecule | MK-0354 | Indication associated | Details |
| R0902 | DB05943 | investigational | small molecule | Resatorvid | Therapeutic strategy associated | Details |
| R0903 | DB05945 | investigational | biotech | MDX-1303 | Indication associated | Details |
| R0904 | DB05959 | investigational | small molecule | ENMD-1198 | Therapeutic strategy associated | Details |
| R0905 | DB05964 | investigational | small molecule | Amitifadine | Indication associated | Details |
| R0906 | DB05968 | investigational | small molecule | PR-104 | Therapeutic strategy associated | Details |
| R0907 | DB05969 | investigational | small molecule | SNS-032 | Therapeutic strategy associated | Details |
| R0908 | DB05971 | investigational | small molecule | Archexin | Therapeutic strategy associated | Details |
| R0909 | DB05973 | investigational | small molecule | Inosine 5'-sulfate | Indication associated | Details |
| R0910 | DB05974 | investigational | small molecule | Transcrocetinate | Indication associated | Details |
| R0911 | DB05983 | investigational | small molecule | Bardoxolone methyl | Therapeutic strategy associated | Details |
| R0912 | DB05992 | investigational | small molecule | Plinabulin | Target associated | Details |
| R0913 | DB05993 | investigational | small molecule | PRX-07034 | Therapeutic strategy associated | Details |
| R0914 | DB06011 | investigational | small molecule | AMG-222 | Indication associated | Details |
| R0915 | DB06040 | investigational | small molecule | Filanesib | Therapeutic strategy associated | Details |
| R0916 | DB06042 | investigational | small molecule | ZEN-012 | Therapeutic strategy associated | Details |
| R0917 | DB06045 | investigational | small molecule | Trofinetide | Therapeutic strategy associated | Details |
| R0918 | DB06050 | investigational | biotech | TB-402 | Indication associated | Details |
| R0919 | DB06075 | investigational | small molecule | Linsitinib | Therapeutic strategy associated | Details |
| R0920 | DB06080 | investigational | small molecule | Linifanib | Therapeutic strategy associated | Details |
| R0921 | DB06081 | approved; investigational | biotech | Caplacizumab | Therapeutic strategy associated | Details |
| R0922 | DB06082 | investigational | small molecule | PX-478 | Therapeutic strategy associated | Details |
| R0923 | DB06087 | investigational | small molecule | Friulimicin B | Indication associated | Details |
| R0924 | DB06094 | investigational | small molecule | Apatorsen | Therapeutic strategy associated | Details |
| R0925 | DB06097 | investigational | small molecule | GSK-923295 | Therapeutic strategy associated | Details |
| R0926 | DB06101 | investigational | biotech | IMC-1C11 | Therapeutic strategy associated | Details |
| R0927 | DB06111 | experimental | small molecule | AB192 | Indication associated | Details |
| R0928 | DB06127 | investigational | small molecule | Bisegliptin | Indication associated | Details |
| R0929 | DB06137 | approved; investigational | small molecule | Tirbanibulin | Therapeutic strategy associated | Details |
| R0930 | DB06148 | approved; investigational | small molecule | Mianserin | Indication associated | Details |
| R0931 | DB06149 | approved; investigational | small molecule | Teicoplanin | Indication associated | Details |
| R0932 | DB06152 | approved | small molecule | Nylidrin | Indication associated | Details |
| R0933 | DB06154 | approved | small molecule | Pentaerythritol tetranitrate | Therapeutic strategy associated | Details |
| R0934 | DB06156 | investigational | small molecule | Tesofensine | Indication associated | Details |
| R0935 | DB06160 | investigational | small molecule | Garenoxacin | Indication associated | Details |
| R0936 | DB06168 | approved; investigational | biotech | Canakinumab | Therapeutic strategy associated | Details |
| R0937 | DB06176 | approved; investigational | small molecule | Romidepsin | Therapeutic strategy associated | Details |
| R0938 | DB06190 | investigational | small molecule | Solabegron | Indication associated | Details |
| R0939 | DB06193 | approved; investigational | small molecule | Pixantrone | Therapeutic strategy associated | Details |
| R0940 | DB06200 | investigational | small molecule | Tedisamil | Indication associated | Details |
| R0941 | DB06202 | approved; investigational | small molecule | Lasofoxifene | Indication associated | Details |
| R0942 | DB06203 | approved | small molecule | Alogliptin | Indication associated | Details |
| R0943 | DB06204 | approved | small molecule | Tapentadol | Indication associated | Details |
| R0944 | DB06207 | approved | small molecule | Silodosin | Therapeutic strategy associated | Details |
| R0945 | DB06209 | approved | small molecule | Prasugrel | Therapeutic strategy associated | Details |
| R0946 | DB06217 | approved; investigational | small molecule | Vernakalant | Indication associated | Details |
| R0947 | DB06224 | investigational | small molecule | Alicaforsen | Therapeutic strategy associated | Details |
| R0948 | DB06225 | investigational | small molecule | HMR4011 | Therapeutic strategy associated | Details |
| R0949 | DB06228 | approved | small molecule | Rivaroxaban | Indication associated | Details |
| R0950 | DB06231 | investigational | small molecule | Caldaret | Indication associated | Details |
| R0951 | DB06237 | approved | small molecule | Avanafil | Therapeutic strategy associated | Details |
| R0952 | DB06241 | investigational | biotech | Clenoliximab | Indication associated | Details |
| R0953 | DB06244 | investigational | biotech | Trafermin | Indication associated | Details |
| R0954 | DB06245 | investigational | biotech | Lanoteplase | Indication associated | Details |
| R0955 | DB06246 | investigational | small molecule | Exisulind | Therapeutic strategy associated | Details |
| R0956 | DB06248 | investigational | small molecule | Amelubant | Indication associated | Details |
| R0957 | DB06249 | approved; investigational | small molecule | Arzoxifene | Indication associated | Details |
| R0958 | DB06250 | investigational | small molecule | Fluasterone | Therapeutic strategy associated | Details |
| R0959 | DB06253 | investigational | small molecule | Thioctic acid tromethamine | Indication associated | Details |
| R0960 | DB06255 | experimental | small molecule | Incadronic acid | Therapeutic strategy associated | Details |
| R0961 | DB06256 | investigational | biotech | rPSGL-Ig | Indication associated | Details |
| R0962 | DB06257 | investigational | small molecule | HE-2200 | Indication associated | Details |
| R0963 | DB06263 | investigational | small molecule | Amrubicin | Therapeutic strategy associated | Details |
| R0964 | DB06266 | investigational | small molecule | Lonidamine | Therapeutic strategy associated | Details |
| R0965 | DB06267 | approved; investigational | small molecule | Udenafil | Indication associated | Details |
| R0966 | DB06268 | approved; investigational; withdrawn | small molecule | Sitaxentan | Indication associated | Details |
| R0967 | DB06270 | investigational | small molecule | MAHDL01 | Indication associated | Details |
| R0968 | DB06271 | approved; investigational | biotech | Sulodexide | Therapeutic strategy associated | Details |
| R0969 | DB06273 | approved | biotech | Tocilizumab | Therapeutic strategy associated | Details |
| R0970 | DB06276 | investigational | small molecule | Tanomastat | Indication associated | Details |
| R0971 | DB06281 | investigational | small molecule | Torcetrapib | Indication associated | Details |
| R0972 | DB06283 | approved | small molecule | Ziconotide | Therapeutic strategy associated | Details |
| R0973 | DB06285 | approved; investigational | biotech | Teriparatide | Indication associated | Details |
| R0974 | DB06287 | approved | small molecule | Temsirolimus | Indication associated | Details |
| R0975 | DB06297 | investigational | small molecule | LX-2931 | Indication associated | Details |
| R0976 | DB06307 | investigational | small molecule | Apoptone | Therapeutic strategy associated | Details |
| R0977 | DB06309 | investigational | small molecule | Refametinib | Therapeutic strategy associated | Details |
| R0978 | DB06311 | investigational | small molecule | Darapladib | Therapeutic strategy associated | Details |
| R0979 | DB06314 | investigational | small molecule | SGX-523 | Therapeutic strategy associated | Details |
| R0980 | DB06323 | investigational | biotech | AZX-100 | Therapeutic strategy associated | Details |
| R0981 | DB06324 | investigational | biotech | XmAb 2513 | Target associated | Details |
| R0982 | DB06326 | investigational | biotech | Latiglutenase | Indication associated | Details |
| R0983 | DB06329 | investigational | small molecule | RG-7795 | Therapeutic strategy associated | Details |
| R0984 | DB06333 | investigational | small molecule | Trodusquemine | Therapeutic strategy associated | Details |
| R0985 | DB06335 | approved | small molecule | Saxagliptin | Indication associated | Details |
| R0986 | DB06343 | approved; investigational | biotech | Teprotumumab | Therapeutic strategy associated | Details |
| R0987 | DB06345 | investigational | small molecule | AR-9281 | Therapeutic strategy associated | Details |
| R0988 | DB06346 | investigational | small molecule | Fiboflapon | Therapeutic strategy associated | Details |
| R0989 | DB06347 | investigational | small molecule | Cenisertib | Therapeutic strategy associated | Details |
| R0990 | DB06350 | investigational | small molecule | Elinogrel | Indication associated | Details |
| R0991 | DB06358 | investigational | small molecule | Iclaprim | Indication associated | Details |
| R0992 | DB06360 | investigational | biotech | Lucatumumab | Target associated | Details |
| R0993 | DB06362 | investigational | small molecule | Becatecarin | Therapeutic strategy associated | Details |
| R0994 | DB06366 | approved | biotech | Pertuzumab | Therapeutic strategy associated | Details |
| R0995 | DB06367 | investigational | small molecule | Relacatib | Indication associated | Details |
| R0996 | DB06372 | approved; investigational | biotech | Rilonacept | Therapeutic strategy associated | Details |
| R0997 | DB06376 | investigational | small molecule | CHGN111 | Therapeutic strategy associated | Details |
| R0998 | DB06379 | investigational | biotech | Calcitonin gene-related peptide | Therapeutic strategy associated | Details |
| R0999 | DB06395 | investigational | small molecule | Abafungin | Indication associated | Details |
| R1000 | DB06397 | investigational | small molecule | Nicaraven | Indication associated | Details |