CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of NAFLD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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34330 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C01104 | BRD-A45107007 | salubrinal | EIF2S1 | Eukaryotic translation initiation factor inhibitor | -- | Details |
| C01105 | BRD-A45134043 | BRD-A45134043 | -- | -- | -- | Details |
| C01106 | BRD-A45140972 | meclocycline | -- | -- | -- | Details |
| C01107 | BRD-A45153512 | bimatoprost | PTGFR | Prostanoid receptor agonist | -- | Details |
| C01108 | BRD-A45206415 | BRD-A45206415 | -- | -- | -- | Details |
| C01109 | BRD-A45333398 | periplocymarin | -- | -- | -- | Details |
| C01110 | BRD-A45349889 | BRD-A45349889 | -- | -- | -- | Details |
| C01111 | BRD-A45498368 | WYE-125132 | MTOR | MTOR inhibitor | -- | Details |
| C01112 | BRD-A45499626 | UBP-302 | GRIK1 | Glutamate receptor antagonist | -- | Details |
| C01113 | BRD-A45524355 | BRD-A45524355 | -- | -- | -- | Details |
| C01114 | BRD-A45540146 | KI-20227 | -- | -- | -- | Details |
| C01115 | BRD-A45543382 | metrizamide | -- | -- | -- | Details |
| C01116 | BRD-A45607610 | BRD-A45607610 | -- | -- | -- | Details |
| C01117 | BRD-A45657137 | BRD-A45657137 | -- | -- | -- | Details |
| C01118 | BRD-A45664787 | iloprost | PTGER1; PTGER2; PTGIR | Prostanoid receptor agonist; Platelet aggregation inhibitor | -- | Details |
| C01119 | BRD-A45869167 | SAL-003 | -- | -- | -- | Details |
| C01120 | BRD-A45889380 | mepacrine | TP53 | TP53 activator; NFKB pathway inhibitor; Cytokine production inhibitor | -- | Details |
| C01121 | BRD-A46066006 | clidinium | CHRM1 | Acetylcholine receptor antagonist | -- | Details |
| C01122 | BRD-A46179541 | doxapram | KCNK3; KCNK9 | Potassium channel blocker | -- | Details |
| C01123 | BRD-A46186775 | hydrocortisone-phosphate | -- | -- | -- | Details |
| C01124 | BRD-A46317335 | BRD-A46317335 | -- | -- | -- | Details |
| C01125 | BRD-A46335897 | promethazine | HRH1 | Histamine receptor antagonist | -- | Details |
| C01126 | BRD-A46393198 | tetramisole | -- | -- | -- | Details |
| C01127 | BRD-A46566149 | BRD-A46566149 | -- | -- | -- | Details |
| C01128 | BRD-A46631350 | BRD-A46631350 | -- | -- | -- | Details |
| C01129 | BRD-A46684810 | colchicine | TUBB; TUBB1 | Microtubule inhibitor | -- | Details |
| C01130 | BRD-A46747628 | ouabain | ATP1A1 | ATPase inhibitor | -- | Details |
| C01131 | BRD-A46778020 | BRD-A46778020 | -- | -- | -- | Details |
| C01132 | BRD-A46802340 | BRD-A46802340 | -- | -- | -- | Details |
| C01133 | BRD-A46950333 | BRD-A46950333 | -- | -- | -- | Details |
| C01134 | BRD-A47065382 | huperzine-a | ACHE | Glutamate receptor antagonist; Acetylcholinesterase inhibitor | -- | Details |
| C01135 | BRD-A47109850 | BRD-A47109850 | -- | -- | -- | Details |
| C01136 | BRD-A47137250 | BRD-A47137250 | -- | -- | -- | Details |
| C01137 | BRD-A47144777 | BRD-A47144777 | -- | -- | dihydro-7-desacetyldeoxygedunin | Details |
| C01138 | BRD-A47166394 | BRD-A47166394 | -- | -- | -- | Details |
| C01139 | BRD-A47268303 | garcinol | -- | -- | -- | Details |
| C01140 | BRD-A47324566 | BRD-A47324566 | -- | -- | -- | Details |
| C01141 | BRD-A47342814 | naltrindole | OPRD1 | Opioid receptor antagonist | -- | Details |
| C01142 | BRD-A47364545 | BRD-A47364545 | -- | -- | SK&F-10047-(+) | Details |
| C01143 | BRD-A47416464 | BRD-A47416464 | -- | -- | -- | Details |
| C01144 | BRD-A47428621 | BRD-A47428621 | -- | -- | -- | Details |
| C01145 | BRD-A47441220 | mevalonic-acid | -- | -- | -- | Details |
| C01146 | BRD-A47449001 | ipratropium | CHRM1; CHRM2; CHRM3; CHRM4 | Acetylcholine receptor antagonist | ipratropium-br | Details |
| C01147 | BRD-A47494775 | dipivefrine | ADRA1A | Adrenergic receptor agonist | -- | Details |
| C01148 | BRD-A47513740 | calyculin | PPP1CA; PPP2CA | Protein phosphatase inhibitor | -- | Details |
| C01149 | BRD-A47564106 | tetrabenazine | SLC18A2 | Vesicular monoamine transporter inhibitor | -- | Details |
| C01150 | BRD-A47598013 | citalopram | SLC6A4 | Serotonin reuptake inhibitor | -- | Details |
| C01151 | BRD-A47615980 | BRD-A47615980 | -- | -- | -- | Details |
| C01152 | BRD-A47633927 | NPC-15199 | -- | -- | -- | Details |
| C01153 | BRD-A47706533 | l-bso | -- | -- | buthionine-sulfoximine | Details |
| C01154 | BRD-A47714657 | BRD-A47714657 | -- | -- | -- | Details |
| C01155 | BRD-A47798787 | BRD-A47798787 | -- | -- | -- | Details |
| C01156 | BRD-A47816767 | BRD-A47816767 | -- | -- | -- | Details |
| C01157 | BRD-A47829399 | artesunate | -- | -- | -- | Details |
| C01158 | BRD-A47832959 | BRD-A47832959 | -- | -- | -- | Details |
| C01159 | BRD-A47884604 | cyanopindolol | ADRB1; HTR1A | Adrenergic receptor antagonist | -- | Details |
| C01160 | BRD-A47963183 | BRD-A47963183 | -- | -- | -- | Details |
| C01161 | BRD-A48015106 | BRD-A48015106 | -- | -- | 8-hydroxy-DPAT | Details |
| C01162 | BRD-A48052484 | BRD-A48052484 | -- | -- | -- | Details |
| C01163 | BRD-A48180038 | trihexyphenidyl | CHRM1 | Acetylcholine receptor antagonist | -- | Details |
| C01164 | BRD-A48228341 | BRD-A48228341 | -- | -- | -- | Details |
| C01165 | BRD-A48237631 | mitomycin-c | -- | -- | -- | Details |
| C01166 | BRD-A48257147 | PHCCC | GRM1; GRM4 | Glutamate receptor agonist | -- | Details |
| C01167 | BRD-A48261811 | argatroban | F2 | Thrombin inhibitor | -- | Details |
| C01168 | BRD-A48300215 | ajmaline | -- | -- | -- | Details |
| C01169 | BRD-A48323445 | salsoline | -- | -- | -- | Details |
| C01170 | BRD-A48349196 | BRD-A48349196 | -- | -- | nor-1-chlorpromazine | Details |
| C01171 | BRD-A48376327 | igmesine | -- | -- | -- | Details |
| C01172 | BRD-A48430263 | pioglitazone | PPARG | Insulin sensitizer; PPAR receptor agonist | -- | Details |
| C01173 | BRD-A48478073 | BRD-A48478073 | -- | -- | -- | Details |
| C01174 | BRD-A48570745 | ivermectin | -- | -- | -- | Details |
| C01175 | BRD-A48631911 | mibefradil | CACNA1C; CACNA1I; CACNA1H; CACNA1G | T-type calcium channel blocker | -- | Details |
| C01176 | BRD-A48720949 | testosterone-propionate | AR | Androgen receptor agonist | -- | Details |
| C01177 | BRD-A48809242 | IB-MECA | ADORA3 | Adenosine receptor agonist | -- | Details |
| C01178 | BRD-A48881734 | BRD-A48881734 | -- | -- | -- | Details |
| C01179 | BRD-A48913311 | BRD-A48913311 | -- | -- | -- | Details |
| C01180 | BRD-A49035384 | metacycline | -- | -- | -- | Details |
| C01181 | BRD-A49046702 | SKF-89976A | SLC6A1 | GABA uptake inhibitor | -- | Details |
| C01182 | BRD-A49148672 | galantamine | ACHE; BCHE | Acetylcholinesterase inhibitor | -- | Details |
| C01183 | BRD-A49160188 | donepezil | ACHE | Acetylcholinesterase inhibitor | -- | Details |
| C01184 | BRD-A49172652 | lansoprazole | ATP4A | ATPase inhibitor | -- | Details |
| C01185 | BRD-A49225603 | alimemazine | HRH1 | Histamine receptor ligand; Histamine receptor agonist | -- | Details |
| C01186 | BRD-A49358627 | ciprofibrate | PPARA | PPAR receptor agonist | -- | Details |
| C01187 | BRD-A49370193 | Ro-60-0175 | HTR2A; HTR2B; HTR2C | Serotonin receptor agonist | -- | Details |
| C01188 | BRD-A49399758 | desmopressin-acetate | AVPR1A; AVPR1B; AVPR2 | Vasopressin receptor agonist | -- | Details |
| C01189 | BRD-A49447682 | BRD-A49447682 | -- | -- | desoximetasone | Details |
| C01190 | BRD-A49544621 | BRD-A49544621 | -- | -- | AC-7954-(+/-) | Details |
| C01191 | BRD-A49581300 | BRD-A49581300 | -- | -- | -- | Details |
| C01192 | BRD-A49622760 | faropenem | -- | -- | -- | Details |
| C01193 | BRD-A49680073 | BRD-A49680073 | -- | -- | cucurbitacin-i | Details |
| C01194 | BRD-A49734948 | foliosidine | -- | -- | -- | Details |
| C01195 | BRD-A49765801 | BRD-A49765801 | -- | -- | fludroxycortide | Details |
| C01196 | BRD-A49838158 | phenprocoumon | VKORC1 | Vitamin K antagonist | -- | Details |
| C01197 | BRD-A49848186 | BRD-A49848186 | -- | -- | -- | Details |
| C01198 | BRD-A49906757 | BRD-A49906757 | -- | -- | scopolamine-n-oxide | Details |
| C01199 | BRD-A50028488 | TCS-2002 | -- | -- | -- | Details |
| C01200 | BRD-A50033377 | rivaroxaban | F10 | Coagulation factor inhibitor | -- | Details |
| C01201 | BRD-A50064262 | flumethasone-pivalate | -- | -- | flumethazone-pivalate | Details |
| C01202 | BRD-A50157456 | terbutaline | ADRB2 | Adrenergic receptor agonist | -- | Details |
| C01203 | BRD-A50287119 | sirolimus | FKBP1A; MTOR | MTOR inhibitor | -- | Details |