CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of NAFLD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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34330 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C00404 | BRD-A15914070 | BRD-A15914070 | -- | -- | 4-hydroxy-2-nonenal | Details |
| C00405 | BRD-A15931911 | bucladesine | PRKACA | CAMP stimulant; Adenosine receptor agonist | -- | Details |
| C00406 | BRD-A16035238 | SAR405838 | MDM2 | MDM inhibitor | -- | Details |
| C00407 | BRD-A16119053 | BRD-A16119053 | -- | -- | -- | Details |
| C00408 | BRD-A16296925 | indobufen | PTGS1; PTGS2 | Cyclooxygenase inhibitor; Platelet aggregation inhibitor | -- | Details |
| C00409 | BRD-A16311756 | profenamine | CHRM1 | Butyrylcholinesterase inhibitor; Cholinergic receptor antagonist | -- | Details |
| C00410 | BRD-A16313205 | BRD-A16313205 | -- | -- | -- | Details |
| C00411 | BRD-A16332958 | modafinil | SLC6A3 | Adrenergic receptor agonist | -- | Details |
| C00412 | BRD-A16347691 | thioctic-acid | -- | -- | -- | Details |
| C00413 | BRD-A16444946 | acarbose | GAA; AMY2A; MGAM | Glucosidase inhibitor | -- | Details |
| C00414 | BRD-A16478930 | amcinonide | NR3C1 | Glucocorticoid receptor agonist | -- | Details |
| C00415 | BRD-A16581344 | BRD-A16581344 | -- | -- | -- | Details |
| C00416 | BRD-A16665823 | butoconazole | -- | -- | -- | Details |
| C00417 | BRD-A16694057 | BADGE | PPARG | PPAR receptor antagonist | badge | Details |
| C00418 | BRD-A16700644 | isoxsuprine | ADRB2 | Adrenergic receptor agonist | -- | Details |
| C00419 | BRD-A16746338 | BRD-A16746338 | -- | -- | podophyllotoxin | Details |
| C00420 | BRD-A16754160 | ampicillin | -- | -- | -- | Details |
| C00421 | BRD-A16760970 | BRD-A16760970 | -- | -- | -- | Details |
| C00422 | BRD-A16820783 | BRD-A16820783 | -- | -- | -- | Details |
| C00423 | BRD-A16827030 | BRD-A16827030 | -- | -- | -- | Details |
| C00424 | BRD-A16934955 | nalbuphine | OPRD1; OPRK1; OPRM1 | Opioid receptor agonist; Opioid receptor antagonist | -- | Details |
| C00425 | BRD-A16997652 | protirelin | TRHR | Thyrotropin releasing hormone receptor agonist | -- | Details |
| C00426 | BRD-A16998493 | etodolac | PTGS2 | Cyclooxygenase inhibitor | -- | Details |
| C00427 | BRD-A17016119 | rhizocarpic-acid | -- | -- | -- | Details |
| C00428 | BRD-A17043706 | BRD-A17043706 | -- | -- | -- | Details |
| C00429 | BRD-A17065207 | brefeldin-a | -- | -- | -- | Details |
| C00430 | BRD-A17081056 | BRD-A17081056 | -- | -- | -- | Details |
| C00431 | BRD-A17120244 | BRD-A17120244 | -- | -- | -- | Details |
| C00432 | BRD-A17369009 | BRD-A17369009 | -- | -- | -- | Details |
| C00433 | BRD-A17390249 | BG-1015 | -- | -- | -- | Details |
| C00434 | BRD-A17411484 | carprofen | PTGS1; PTGS2 | Cyclooxygenase inhibitor | -- | Details |
| C00435 | BRD-A17428743 | BW-723C86 | HTR2B | Serotonin receptor agonist | -- | Details |
| C00436 | BRD-A17448384 | beclometasone | NR3C1 | Glucocorticoid receptor agonist | -- | Details |
| C00437 | BRD-A17453586 | MDL-72832 | HTR1A | Serotonin receptor agonist | -- | Details |
| C00438 | BRD-A17462676 | bambuterol | ADRB2 | Adrenergic receptor agonist | -- | Details |
| C00439 | BRD-A17535965 | gelsemine | GLRA3 | Glycine receptor antagonist; Acetylcholine receptor antagonist | -- | Details |
| C00440 | BRD-A17555397 | beta-alanine | -- | -- | -- | Details |
| C00441 | BRD-A17635048 | BRD-A17635048 | -- | -- | -- | Details |
| C00442 | BRD-A17655518 | ibuprofen | PTGS1; PTGS2 | Cyclooxygenase inhibitor | -- | Details |
| C00443 | BRD-A17658676 | BRD-A17658676 | -- | -- | -- | Details |
| C00444 | BRD-A17664363 | BRD-A17664363 | NR5A1 | Steroidogenic factor antagonist | -- | Details |
| C00445 | BRD-A17687311 | BRD-A17687311 | -- | -- | -- | Details |
| C00446 | BRD-A17718497 | BRD-A17718497 | -- | -- | -- | Details |
| C00447 | BRD-A17741195 | BRD-A17741195 | -- | -- | -- | Details |
| C00448 | BRD-A17745711 | alpha-methylserotonin | -- | -- | -- | Details |
| C00449 | BRD-A17757596 | BRD-A17757596 | -- | -- | -- | Details |
| C00450 | BRD-A17818859 | BRD-A17818859 | -- | -- | -- | Details |
| C00451 | BRD-A17819071 | gedunin | HSP90AA1 | HSP inhibitor | -- | Details |
| C00452 | BRD-A17828570 | fulvestrant | ESR1 | Estrogen receptor antagonist | -- | Details |
| C00453 | BRD-A17831693 | BRD-A17831693 | -- | -- | -- | Details |
| C00454 | BRD-A17846016 | trolox | -- | -- | -- | Details |
| C00455 | BRD-A17883755 | lenalidomide | CRBN; TNF | Anti-cancer agent | -- | Details |
| C00456 | BRD-A17902629 | BRD-A17902629 | -- | -- | -- | Details |
| C00457 | BRD-A18043272 | phensuximide | -- | -- | -- | Details |
| C00458 | BRD-A18202423 | CPCCOEt | GRM1 | Glutamate receptor antagonist | cpccoet | Details |
| C00459 | BRD-A18246003 | monoethylhexylphthalate | -- | -- | -- | Details |
| C00460 | BRD-A18279961 | TEPP-46 | -- | -- | -- | Details |
| C00461 | BRD-A18328003 | GDC-0980 | MTOR; PIK3CG | MTOR inhibitor; PI3K inhibitor | -- | Details |
| C00462 | BRD-A18411371 | BRD-A18411371 | -- | -- | -- | Details |
| C00463 | BRD-A18419789 | etoposide | TOP2A; TOP2B | Topoisomerase inhibitor | -- | Details |
| C00464 | BRD-A18477699 | BRD-A18477699 | -- | -- | -- | Details |
| C00465 | BRD-A18497530 | 5-iodotubercidin | MAPK3 | Adenosine kinase inhibitor | 5-IODOTUBERCIDIN | Details |
| C00466 | BRD-A18573497 | BRD-A18573497 | -- | -- | -- | Details |
| C00467 | BRD-A18579359 | wiskostatin | WASL | Neural Wiskott-Aldrich syndrome protein inhibitor | -- | Details |
| C00468 | BRD-A18605525 | hexetidine | -- | -- | -- | Details |
| C00469 | BRD-A18611368 | tazobactam | -- | -- | -- | Details |
| C00470 | BRD-A18620900 | estriol | ESR1; ESR2 | Estrogen receptor agonist | -- | Details |
| C00471 | BRD-A18696154 | idazoxan | ADRA2A | Adrenergic receptor antagonist | -- | Details |
| C00472 | BRD-A18705706 | BRD-A18705706 | -- | -- | -- | Details |
| C00473 | BRD-A18725729 | BRD-A18725729 | -- | -- | -- | Details |
| C00474 | BRD-A18763547 | BRD-A18763547 | -- | -- | BAX-channel-blocker | Details |
| C00475 | BRD-A18795974 | BRD-A18795974 | -- | -- | 7-hydroxy-DPAT | Details |
| C00476 | BRD-A18825024 | BRD-A18825024 | -- | -- | -- | Details |
| C00477 | BRD-A18917088 | estradiol | ESR1; ESR2; NR1I2 | Estrogen receptor agonist | -- | Details |
| C00478 | BRD-A18929998 | cytarabine | POLA1; POLB | Ribonucleotide reductase inhibitor | -- | Details |
| C00479 | BRD-A18932057 | haematoxylin-pentaacetate | -- | -- | -- | Details |
| C00480 | BRD-A18945128 | BRD-A18945128 | -- | -- | -- | Details |
| C00481 | BRD-A19037878 | BRD-A19037878 | -- | -- | trichostatin-a | Details |
| C00482 | BRD-A19053259 | pseudopelletierine | -- | -- | -- | Details |
| C00483 | BRD-A19078268 | BRD-A19078268 | -- | -- | -- | Details |
| C00484 | BRD-A19102171 | naltriben | OPRD1 | Opioid receptor antagonist | -- | Details |
| C00485 | BRD-A19134330 | A-23187 | -- | -- | -- | Details |
| C00486 | BRD-A19195498 | trimipramine | SLC6A2; SLC6A3; SLC6A4 | Tricyclic antidepressant; Norepinephrine reputake inhibitor | -- | Details |
| C00487 | BRD-A19231254 | BRD-A19231254 | -- | -- | -- | Details |
| C00488 | BRD-A19232309 | BRD-A19232309 | -- | -- | 1,2-propylene-glycol | Details |
| C00489 | BRD-A19248578 | latrunculin-b | -- | -- | -- | Details |
| C00490 | BRD-A19374631 | vinpocetine | PDE1A | Sodium channel blocker; Phosphodiesterase inhibitor | -- | Details |
| C00491 | BRD-A19500257 | geldanamycin | HSP90AA1 | HSP inhibitor | -- | Details |
| C00492 | BRD-A19585813 | methylphenidate | SLC6A2; SLC6A3 | Dopamine-norepinephrine reuptake inhibitor | -- | Details |
| C00493 | BRD-A19615705 | BRD-A19615705 | -- | -- | -- | Details |
| C00494 | BRD-A19633847 | perhexiline | CPT1A; CPT2 | Carnitine palmitoyltransferase inhibitor | -- | Details |
| C00495 | BRD-A19661776 | mianserin | ADRA1D; ADRA1B; ADRA1A; DRD2; HRH1; HTR1A; HTR2A; HTR2B; HTR2C; HTR6; HTR7 | Serotonin receptor antagonist | -- | Details |
| C00496 | BRD-A19736161 | ondansetron | HTR3A | Serotonin receptor antagonist | -- | Details |
| C00497 | BRD-A19766589 | BRD-A19766589 | -- | -- | -- | Details |
| C00498 | BRD-A19795905 | atovaquone | -- | -- | -- | Details |
| C00499 | BRD-A19829191 | BRD-A19829191 | -- | -- | -- | Details |
| C00500 | BRD-A19912945 | BRD-A19912945 | -- | -- | -- | Details |
| C00501 | BRD-A19918940 | lomatin | -- | -- | -- | Details |
| C00502 | BRD-A19928752 | BRD-A19928752 | -- | -- | -- | Details |
| C00503 | BRD-A19952358 | closantel | -- | -- | -- | Details |