CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of NAFLD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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34330 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C01404 | BRD-A58937872 | BRD-A58937872 | -- | -- | -- | Details |
| C01405 | BRD-A58955223 | sulforaphane | NFE2L2 | Anti-cancer agent; Aryl hydrocarbon receptor antagonist | -- | Details |
| C01406 | BRD-A59001851 | ginkgolide-b | GLRA1; GLRB; PTAFR | Reducing agent; Immunosuppressant; Protease inhibitor; Peptidase inhibitor; GABA receptor antagonist; Glycine receptor antagonist; Platelet activating factor receptor antagonist | -- | Details |
| C01407 | BRD-A59009217 | BRD-A59009217 | -- | -- | -- | Details |
| C01408 | BRD-A59046243 | BRD-A59046243 | -- | -- | -- | Details |
| C01409 | BRD-A59145032 | BRD-A59145032 | -- | -- | -- | Details |
| C01410 | BRD-A59158939 | BRD-A59158939 | -- | -- | -- | Details |
| C01411 | BRD-A59174698 | ritodrine | ADRB2 | Adrenergic receptor agonist | -- | Details |
| C01412 | BRD-A59193861 | K784-3391 | -- | -- | K-784-3391 | Details |
| C01413 | BRD-A59198242 | viloxazine | SLC6A2 | Serotonin reuptake inhibitor | -- | Details |
| C01414 | BRD-A59215453 | lobelanidine | OPRM1; SLC18A2 | Opioid receptor antagonist; Dopamine receptor modulator; Acetylcholine receptor antagonist; Vesicular monoamine transporter ligand | -- | Details |
| C01415 | BRD-A59303141 | quinethazone | SLC12A3 | Thiazide diuretic | -- | Details |
| C01416 | BRD-A59337442 | xamoterol | ADRB1 | Adrenergic receptor agonist | -- | Details |
| C01417 | BRD-A59391763 | BRD-A59391763 | -- | -- | -- | Details |
| C01418 | BRD-A59431241 | COL-3 | -- | -- | -- | Details |
| C01419 | BRD-A59449038 | BRD-A59449038 | -- | -- | -- | Details |
| C01420 | BRD-A59468452 | BRD-A59468452 | -- | -- | -- | Details |
| C01421 | BRD-A59682351 | BRD-A59682351 | -- | -- | -- | Details |
| C01422 | BRD-A59683007 | BRD-A59683007 | -- | -- | -- | Details |
| C01423 | BRD-A59709458 | PHCCC | GRM1; GRM4 | Glutamate receptor agonist | -- | Details |
| C01424 | BRD-A59728941 | BRD-A59728941 | -- | -- | -- | Details |
| C01425 | BRD-A59808129 | guggulsterone | NR3C1; AR; NR3C2; PGR; NR1H4 | IKK inhibitor; FXR antagonist; Cholesterol inhibitor; Estrogen receptor agonist; Pregnane X receptor agonist; Progesterone receptor agonist | -- | Details |
| C01426 | BRD-A59900482 | VU-0415533-1 | -- | -- | -- | Details |
| C01427 | BRD-A59943784 | fluticasone | NR3C1; PGR | Glucocorticoid receptor agonist | -- | Details |
| C01428 | BRD-A59985574 | topotecan | TOP1 | Topoisomerase inhibitor | -- | Details |
| C01429 | BRD-A59995060 | BRD-A59995060 | -- | -- | -- | Details |
| C01430 | BRD-A60052764 | flucloxacillin | -- | -- | -- | Details |
| C01431 | BRD-A60070924 | alpha-estradiol | ESR1; ESR2; NR1I2 | Estrogen receptor agonist | -- | Details |
| C01432 | BRD-A60076435 | BRD-A60076435 | -- | -- | -- | Details |
| C01433 | BRD-A60091465 | BRD-A60091465 | -- | -- | -- | Details |
| C01434 | BRD-A60197193 | amisulpride | DRD2; DRD3 | Dopamine receptor antagonist | -- | Details |
| C01435 | BRD-A60217728 | iohexol | -- | -- | -- | Details |
| C01436 | BRD-A60245366 | AS-601245 | MAPK8; MAPK9; MAPK10 | JNK inhibitor | -- | Details |
| C01437 | BRD-A60256353 | ST-019386 | -- | -- | -- | Details |
| C01438 | BRD-A60274948 | bromocriptine | ADRA2A; ADRA2B; ADRA2C; DRD1; DRD2; DRD3; DRD4; DRD5; HTR1A; HTR1B; HTR1D; HTR2A; HTR2B; HTR2C | Dopamine receptor agonist | -- | Details |
| C01439 | BRD-A60294240 | tribenoside | -- | -- | -- | Details |
| C01440 | BRD-A60363637 | BRD-A60363637 | -- | -- | -- | Details |
| C01441 | BRD-A60386802 | BRD-A60386802 | -- | -- | -- | Details |
| C01442 | BRD-A60414806 | vincristine | TUBB | Tubulin inhibitor | -- | Details |
| C01443 | BRD-A60487173 | BRD-A60487173 | -- | -- | -- | Details |
| C01444 | BRD-A60513937 | BRD-A60513937 | -- | -- | -- | Details |
| C01445 | BRD-A60571864 | budesonide | NR3C1 | Glucocorticoid receptor agonist | -- | Details |
| C01446 | BRD-A60583491 | nitrarine | -- | -- | -- | Details |
| C01447 | BRD-A60784279 | BRD-A60784279 | -- | -- | -- | Details |
| C01448 | BRD-A60877539 | BRD-A60877539 | -- | -- | -- | Details |
| C01449 | BRD-A61014366 | BRD-A61014366 | -- | -- | -- | Details |
| C01450 | BRD-A61046366 | BRD-A61046366 | -- | -- | -- | Details |
| C01451 | BRD-A61154809 | gliclazide | ABCC8 | ATP channel blocker; Insulin secretagogue | -- | Details |
| C01452 | BRD-A61189834 | BRD-A61189834 | XIAP | XIAP inhibitor | -- | Details |
| C01453 | BRD-A61194565 | benserazide | DDC | DOPA decarboxylase inhibitor | -- | Details |
| C01454 | BRD-A61221616 | medroxyprogesterone-acetate | PGR | Progesterone receptor agonist | -- | Details |
| C01455 | BRD-A61273891 | aflatoxin-b1 | -- | -- | -- | Details |
| C01456 | BRD-A61304759 | tanespimycin | HSP90AA1 | HSP inhibitor | -- | Details |
| C01457 | BRD-A61392169 | eliprodil | GRIN1; GRIN2B | Glutamate receptor antagonist | -- | Details |
| C01458 | BRD-A61470182 | N-formylmethionylalanine | -- | -- | n-formylmethionylalanine | Details |
| C01459 | BRD-A61486721 | apramycin | -- | -- | -- | Details |
| C01460 | BRD-A61522392 | BRD-A61522392 | -- | -- | -- | Details |
| C01461 | BRD-A61599461 | BRD-A61599461 | TSHR | Thyroid-stimulating hormone receptor inverse agonist | -- | Details |
| C01462 | BRD-A61666925 | EMF-sumo1-6 | -- | -- | -- | Details |
| C01463 | BRD-A61676498 | climbazole | -- | -- | -- | Details |
| C01464 | BRD-A61767428 | ursolic-acid | HSD11B1; PTPN1 | STAT inhibitor; ATPase inhibitor; Caspase inhibitor; HIV protease inhibitor; NFKB pathway inhibitor; Lipid peroxidase inhibitor; Steryl sulfatase inhibitor; Acetylcholinesterase inhibitor; Tyrosine phosphatase inhibitor; Quorum sensing signaling modulator; 11-beta hydroxysteroid dehydrogenase inhibitor | -- | Details |
| C01465 | BRD-A61767497 | BRD-A61767497 | -- | -- | -- | Details |
| C01466 | BRD-A61778798 | BRD-A61778798 | -- | -- | -- | Details |
| C01467 | BRD-A61793559 | metolazone | SLC12A3 | Carbonic anhydrase inhibitor | -- | Details |
| C01468 | BRD-A61825514 | BRD-A61825514 | -- | -- | -- | Details |
| C01469 | BRD-A61856038 | tremulacin | -- | -- | -- | Details |
| C01470 | BRD-A61858259 | CAY-10415 | INS | Insulin sensitizer | -- | Details |
| C01471 | BRD-A61864215 | BRD-A61864215 | -- | -- | -- | Details |
| C01472 | BRD-A61866602 | BRD-A61866602 | -- | -- | 5-methoxy-alpha-methyltryptamine | Details |
| C01473 | BRD-A61899133 | catechin | -- | -- | -- | Details |
| C01474 | BRD-A62021152 | WAY-161503 | HTR2C | Serotonin receptor agonist | -- | Details |
| C01475 | BRD-A62025033 | temsirolimus | MTOR | MTOR inhibitor | -- | Details |
| C01476 | BRD-A62035778 | scopolamine | CHRM1; CHRM2; CHRM3; CHRM4 | Acetylcholine receptor antagonist | -- | Details |
| C01477 | BRD-A62057054 | MDL-11939 | HTR2A | Serotonin receptor antagonist | -- | Details |
| C01478 | BRD-A62071884 | siguazodan | PDE3A | Phosphodiesterase inhibitor | -- | Details |
| C01479 | BRD-A62182663 | YK-4279 | DHX9; FLI1 | Apoptosis stimulant; Binding of RNA helicase A to the transcription factor EWS-FLI1 inhibitor | -- | Details |
| C01480 | BRD-A62184259 | cycloheximide | RPL3 | Protein synthesis inhibitor | -- | Details |
| C01481 | BRD-A62200266 | BRD-A62200266 | -- | -- | -- | Details |
| C01482 | BRD-A62209527 | ZM-226600 | -- | -- | -- | Details |
| C01483 | BRD-A62326914 | paroxetine | SLC6A4 | Selective serotonin reuptake inhibitor | -- | Details |
| C01484 | BRD-A62336480 | niguldipine | ADRA1A; CACNA1C | Calcium channel blocker; Adrenergic receptor antagonist | -- | Details |
| C01485 | BRD-A62421304 | mepenzolate | -- | -- | -- | Details |
| C01486 | BRD-A62428732 | hydroxyzine | HRH1 | Antihistamine | -- | Details |
| C01487 | BRD-A62434282 | goserelin | GNRHR | Luteinizing hormone releasing hormone agonist | -- | Details |
| C01488 | BRD-A62469171 | BRD-A62469171 | -- | -- | -- | Details |
| C01489 | BRD-A62496920 | BRD-A62496920 | -- | -- | -- | Details |
| C01490 | BRD-A62505706 | edoxudine | -- | -- | -- | Details |
| C01491 | BRD-A62525898 | prednisone | NR3C1 | Glucocorticoid receptor agonist | -- | Details |
| C01492 | BRD-A62591245 | BRD-A62591245 | -- | -- | -- | Details |
| C01493 | BRD-A62599490 | CLINDAMYCIN-PO4 | -- | -- | -- | Details |
| C01494 | BRD-A62647958 | BRD-A62647958 | -- | -- | -- | Details |
| C01495 | BRD-A62731508 | cortisone | -- | -- | -- | Details |
| C01496 | BRD-A62787624 | BRD-A62787624 | -- | -- | -- | Details |
| C01497 | BRD-A62809825 | thapsigargin | ATP2A1 | ATPase inhibitor | -- | Details |
| C01498 | BRD-A62827252 | 642_4014_9503 | -- | -- | -- | Details |
| C01499 | BRD-A62879835 | rifaximin | NR1I2 | RNA synthesis inhibitor | -- | Details |
| C01500 | BRD-A62890442 | 3-methyl-GABA | ABAT | GABA aminotransferase activator | -- | Details |
| C01501 | BRD-A62995832 | BRD-A62995832 | -- | -- | -- | Details |
| C01502 | BRD-A63043573 | cabergoline | ADRA1A; ADRA2A; ADRA2B; ADRA2C; DRD1; DRD2; DRD3; DRD4; DRD5; HTR1A; HTR1B; HTR1D; HTR2A; HTR2B; HTR2C | Dopamine receptor agonist | -- | Details |
| C01503 | BRD-A63236097 | BRD-A63236097 | -- | -- | andrographolide | Details |